鹽酸金霉素
Chlorotetracycline hydrochloride
Cas 號(hào)： 【64-72-2】 M D L： MFCD00082440
鹽酸金霉素 分子式： C22H23ClN2O8·HCL 分子量： 515.34
別 名： 6-甲基-4- （二甲氨基）-3,6,10,12,12α-五羥基-1,11-二氧代-7- 氯-1,4,4α,5,5α,6,11,12α- 八氫-2-并四苯甲酰胺酸酸鹽
7-Chlorotetracycline hydrochloride
USP級(jí),≥80.0% （HPLC） 100g
USP級(jí),≥80.0% （HPLC） 25g
USP級(jí),≥80.0% （HPLC） 5g
性 狀： 本品為金或結(jié)晶；無臭，味苦；遇光色漸變暗。在水或乙醇中微溶，在丙酮、二氧六環(huán)、丙二醇或氯仿中幾乎不溶，溶于氫氧化物和碳酸鹽堿溶液。溶解度:8.6 g/L 水（28°C）、17.4 g/L 甲醇（28°C）, 1.7 g/L 乙醇（28°C）。
熔點(diǎn)：215℃
比旋度[a]20/D:-250°（c=0.5, H2O）
質(zhì)量標(biāo)準(zhǔn)： 外觀Appearance 結(jié)晶
紅外光譜鑒定Infrared spectrometry 和對(duì)照品匹配
純度Purity ≥80.0% （HPLC）
含量Assay 99.0-101.0% （AT）
水溶性實(shí)驗(yàn)Solubility in Water 溶液透明（2.0%水溶液）
細(xì)菌生長試驗(yàn)Bacterial Growth Test 合格
干燥損失Loss on drying <2 %
效價(jià)potency > 900 ug/mg
比旋光度Specific rotation [a]20/D -235°～ -250°（c=0.5, H2O） 在暗處放置30分鐘后
pH 2.3 - 3.3 （1% 溶液）
貯 存： 2-8℃保存。遮光，密封
用途 細(xì)胞滲透熒光探針，用于測(cè)量內(nèi)質(zhì)網(wǎng)Ca2+ 流量
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